Multiple Metastatic Extra-gastrointestinal Stromal Tumors with Plasmoid Differentiation: A Case Report and Review of Literature

• Published in: Internal Medicine Vol. 62; no. 3; pp. 393 - 398
• Main Authors: Ye, Li-Juan, Li, Kun, Xu, Kai-Min, Yuan, Jing, Ran, Fengming
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01.02.2023; Japan Science and Technology Agency
• Subjects: Case Report; Diagnosis, Differential; extra gastrointestinal stromal tumors; Gastrointestinal Stromal Tumors - pathology; Gastrointestinal tract; Humans; Internal medicine; Magnetic resonance imaging; Male; Mesenchyme; Metastases; Middle Aged; multiple metastatic; Neoplasms, Second Primary - pathology; Pancreas - pathology; plasmoid differentiation; Stomach - pathology; Tumors; multiple metastatic; plasmoid differentiation; case report; extra gastrointestinal stromal tumors
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.9727-22

Extra-gastrointestinal stromal tumors (EGISTs) are rare mesenchymal tumors that arise from the abdominal, pelvic or retroperitoneal region, unrelated to the gastrointestinal tract. However, cases with a plasmoid morphology are extremely rare. we hererin report a 49-year-old man with abdominal pain who underwent magnetic resonance imaging that revealed an irregular tumor (103×71 mm) in size, in the space between stomach and pancreas, diagnosed as an EGISIT, we also reviewed the clinicopathological characteristics and immunohistochemical characteristics, molecular genetic features and differential diagnoses previously reported in the literature.