Detecting biological warfare agents

We developed a fiber-optic, microsphere-based, high-density array composed of 18 species-specific probe microsensors to identify biological warfare agents. We simultaneously identified multiple biological warfare agents in environmental samples by looking at specific probe responses after hybridizat...

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Bibliographic Details
Published inEmerging infectious diseases Vol. 11; no. 10; pp. 1629 - 1632
Main Authors Song, Linan, Ahn, Soohyoun, Walt, David R
Format Journal Article
LanguageEnglish
Published United States U.S. National Center for Infectious Diseases 01.10.2005
Centers for Disease Control and Prevention
Subjects
Bacteria - classification
Bacteria - genetics
Bacteria - isolation & purification
Biological warfare
Biological Warfare - methods
Biological Warfare - prevention & control
Biological weapons
Dispatch
DNA microarray
DNA Probes
Fiber Optic Technology - instrumentation
Fiber Optic Technology - methods
fiber optics
fluorescence
Humans
Identification and classification
microsphere
Microspheres
Oligonucleotide Array Sequence Analysis - instrumentation
Oligonucleotide Array Sequence Analysis - methods
Optical Fibers
Polymerase Chain Reaction - methods
Sensitivity and Specificity
Species Specificity
Testing
Vaccinia virus - classification
Vaccinia virus - genetics
Vaccinia virus - isolation & purification
United States
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Summary:We developed a fiber-optic, microsphere-based, high-density array composed of 18 species-specific probe microsensors to identify biological warfare agents. We simultaneously identified multiple biological warfare agents in environmental samples by looking at specific probe responses after hybridization and response patterns of the multiplexed array.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1080-6040
1080-6059
DOI:10.3201/eid1110.050269