Hints of a Therapeutic Vaccine for Alzheimer's?

In this issue of Neuron, Hock et al. report the cognitive functions of a small number of Alzheimer's disease patients that participated in a clinical trial of immunization with β-amyloid. Patients with serum antibodies against β-amyloid plaques showed a diminished cognitive decline and slowed d...

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Bibliographic Details
Published inNeuron Vol. 38; no. 4; pp. 517 - 518
Main Authors Winblad, Bengt, Blum, Kenneth I
Format Book Review Journal Article
LanguageEnglish
Published United States Elsevier Inc 22.05.2003
Elsevier Limited
Subjects
Alzheimer Disease - immunology
Alzheimer Disease - therapy
Alzheimer's disease
Family medical history
Humans
Hypotheses
Immunotherapy, Active
Medicin och hälsovetenskap
Older people
Pathology
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Summary:In this issue of Neuron, Hock et al. report the cognitive functions of a small number of Alzheimer's disease patients that participated in a clinical trial of immunization with β-amyloid. Patients with serum antibodies against β-amyloid plaques showed a diminished cognitive decline and slowed disease progression. Dangerous meningoencephalitis was present in some patients, as has been previously reported.
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ISSN:0896-6273
1097-4199
DOI:10.1016/S0896-6273(03)00297-6