Evaluation of the Antiviral Activity of Chlorine Dioxide and Sodium Hypochlorite against Feline Calicivirus, Human Influenza Virus, Measles Virus, Canine Distemper Virus, Human Herpesvirus, Human Adenovirus, Canine Adenovirus and Canine Parvovirus

• Published in: Biocontrol Science Vol. 15; no. 2; pp. 45 - 49
• Main Authors: SANEKATA, TAKESHI, FUKUDA, TOSHIAKI, MIURA, TAKANORI, MORINO, HIROFUMI, LEE, CHEOLSUNG, MAEDA, KEN, ARAKI, KAZUKO, OTAKE, TORU, KAWAHATA, TAKUYA, SHIBATA, TAKASHI
• Format: Journal Article
• Language: English
• Published: Japan The Society for Antibacterial and Antifungal Agents, Japan 01.01.2010
• Subjects: Adenovirus; Adenoviruses, Canine - drug effects; Adenoviruses, Human - drug effects; Antiviral activity; Antiviral Agents - pharmacology; Calicivirus, Feline - drug effects; Canine distemper virus; Canine parvovirus; Chlorine Compounds - pharmacology; Chlorine dioxide; Distemper Virus, Canine - drug effects; Feline calicivirus; Herpesvirus 1, Human - drug effects; Human adenovirus; Human herpesvirus; Influenza virus; Measles virus; Measles virus - drug effects; Orthomyxoviridae - drug effects; Oxides - pharmacology; Parvovirus, Canine - drug effects; Sodium hypochlorite; Sodium Hypochlorite - pharmacology; Virus inactivation
• ISSN: 1342-4815; 1884-0205
• DOI: 10.4265/bio.15.45

We evaluated the antiviral activity of a chlorine dioxide gas solution (CD) and sodium hypochlorite (SH) against feline calicivirus, human influenza virus, measles virus, canine distemper virus, human herpesvirus, human adenovirus, canine adenovirus and canine parvovirus. CD at concentrations ranging from 1 to 100 ppm produced potent antiviral activity, inactivating ≥ 99.9% of the viruses with a 15 sec treatment for sensitization. The antiviral activity of CD was approximately10 times higher than that of SH.