Velocity-selective magnetization-prepared non-contrast-enhanced cerebral MR angiography at 3 Tesla: Improved immunity to B0/B1 inhomogeneity
Purpose To develop a Fourier‐transform based velocity‐selective (VS) pulse train that offers improved robustness to B0/B1 inhomogeneity for non‐contrast‐enhanced cerebral MR angiography (MRA) at 3 Tesla (T). Methods VS pulse train I and II with different saturation bands are proposed to incorporate...
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Published in | Magnetic resonance in medicine Vol. 75; no. 3; pp. 1232 - 1241 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Blackwell Publishing Ltd
01.03.2016
Wiley Subscription Services, Inc |
Subjects | |
Online Access | Get full text |
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Summary: | Purpose
To develop a Fourier‐transform based velocity‐selective (VS) pulse train that offers improved robustness to B0/B1 inhomogeneity for non‐contrast‐enhanced cerebral MR angiography (MRA) at 3 Tesla (T).
Methods
VS pulse train I and II with different saturation bands are proposed to incorporate paired and phase cycled refocusing pulses. Their sensitivity to B0/B1 inhomogeneity was estimated through simulation and compared with a single refocused VS pulse train. The implementation was compared to standard time of flight (TOF) among eight healthy subjects.
Results
In contrast to single refocused VS pulse train, the simulated VS profiles from proposed pulse trains indicate much improved immunity to field inhomogeneity in the brain at 3T. Successive application of two identical VS pulse trains yields a better suppression of static tissue at the cost of 20∼30% signal loss within large vessels. Average relative contrast ratios of major cerebral arterial segments applying both pulse train I and II with two preparations are 0.81 ± 0.06 and 0.81 ± 0.05, respectively, significantly higher than 0.67 ± 0.07 of TOF‐MRA. VS MRA, in particular, the pulse train II with the narrower saturation band, depicts more small vessels with slower flow.
Conclusion
VS magnetization‐prepared cerebral MRA was demonstrated among normal subjects on a 3T scanner. Magn Reson Med 75:1232–1241, 2016. © 2015 Wiley Periodicals, Inc. |
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Bibliography: | ArticleID:MRM25764 istex:C80F45447B5C17D2172D6DF5A14494A6B45F207E ark:/67375/WNG-CNR8426V-N NIH - No. K25 HL121192, R00HL106232, P41 EB015909 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0740-3194 1522-2594 |
DOI: | 10.1002/mrm.25764 |