In-hospital mortality among a cohort of cirrhotic patients admitted to a tertiary hospital

• Published in: Saudi journal of gastroenterology Vol. 17; no. 6; pp. 387 - 390
• Main Authors: Alsultan, Mohammad A, Alrshed, Rashed S, Aljumah, Abdulrahman A, Baharoon, Salim A, Arabi, Yaseen M, Aldawood, Abdulaziz S
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.11.2011; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Care and treatment; Cirrhosis; Decision Making; Diagnosis; Female; Follow-Up Studies; Hospital Mortality - trends; Hospitalization; Hospitals; Humans; Inpatients; Liver cirrhosis; Liver Cirrhosis - mortality; Liver Cirrhosis - therapy; Male; MELD score; Middle Aged; Mortality; Original; Patient outcomes; Prognosis; Resuscitation; Retrospective Studies; Risk Factors; Saudi Arabia - epidemiology; Saudi Arabia
• ISSN: 1319-3767; 1998-4049
• DOI: 10.4103/1319-3767.87179

To determine the mortality rate in a cohort of hospitalized patients with cirrhosis and examine their resuscitation status at admission. A retrospective chart review was conducted of patients with cirrhosis who were admitted to a tertiary care hospital in Riyadh, Saudi Arabia, from January 1, 2009, to December 31, 2009. We reviewed 226 cirrhotic patients during the study period. The hospital mortality rate was 35%. A univariate analysis revealed that worse outcomes were seen in patients with advanced age or who had worse child-turcotte-pugh (CPT) scores, worse model for end-stage liver disease (MELD) scores, low albumin and high serum creatinine. Using a multivariate analysis, we found that advanced age (P=0.004) and high MELD (P=0.001) scores were independent risk factors for the mortality of cirrhotic patients. The end-of-life decision were made in 34% of cirrhotic patients, and the majority of deceased patients were "no resuscitation" status (90% vs. 4%, P<0.001). The relatively high mortality in cirrhotic patients admitted for care in a tertiary hospital, Saudi Arabia was comparable to that reported in the literature. Furthermore, end-of-life discussions should be addressed early in the hospitalization of cirrhotic patients.