Secondary Metabolites Produced by Plant Growth-Promoting Bacterial Endophytes

• Published in: Microorganisms (Basel) Vol. 10; no. 10; p. 2008
• Main Authors: Narayanan, Zareen, Glick, Bernard R.
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.10.2022; MDPI
• Subjects: Anti-inflammatory agents; Anticancer properties; Antiinfectives and antibacterials; Antimicrobial agents; Antiviral activity; Antiviral agents; Bacteria; Bioactive compounds; Biotechnology; Chemical compounds; Chemical properties; Chemical synthesis; Drug resistance; Endophytes; Flowers & plants; Host plants; Inflammation; mechanisms; Metabolites; Microorganisms; Natural products; Pathogens; Pharmaceutical research; Pharmacology; Plant growth; plant growth promoting bacteria; Plant metabolites; Plants; Review; Secondary metabolites; Seeds; therapeutic applications; VOCs; Volatile organic compounds; Canada; United States
• ISSN: 2076-2607; 2076-2607
• DOI: 10.3390/microorganisms10102008

There is an increasing interest in the use of beneficial microorganisms as alternatives to chemically synthesized or plant-derived molecules to produce therapeutic agents. Bacterial endophytes are plant-associated microorganisms that can colonize different parts of living plants without causing any diseases. Diverse endophytic bacteria possess the ability to synthesize a wide range of secondary metabolites with unique chemical structures that have been exploited for their anti-microbial, antiviral, anti-cancer, and anti-inflammatory properties. Additionally, production of these bioactive compounds can also benefit the host plant as they may play a significant role in a plant’s interaction with the environment for adaptation and defense. As a result of their significant impact as curative compounds or as precursors to produce new drugs, the biotechnological possibilities of secondary metabolites derived from endophytic bacteria are immense.