Custom-made titanium devices as membranes for bone augmentation in implant treatment: Clinical application and the comparison with conventional titanium mesh

• Published in: Journal of cranio-maxillo-facial surgery Vol. 43; no. 10; pp. 2183 - 2188
• Main Authors: Sumida, Tomoki, Otawa, Naruto, Kamata, YU, Kamakura, Satoshi, Mtsushita, Tomiharu, Kitagaki, Hisashi, Mori, Shigeo, Sasaki, Kiyoyuki, Fujibayashi, Shunsuke, Takemoto, Mitsuru, Yamaguchi, Atsushi, Sohmura, Taiji, Nakamura, Takashi, Mori, Yoshihide
• Format: Journal Article
• Language: English
• Published: Scotland Elsevier Ltd 01.12.2015
• Subjects: Bone Regeneration; Clinical trial; Computer aided design; Computer-Aided Design - instrumentation; Custom-made device; Dentistry; Guided bone regeneration; Humans; Prostheses and Implants; Rapid prototyping; Selective laser melting; Surgery; Surgical Mesh; Titanium - chemistry; Titanium - therapeutic use; Clinical trial; Rapid prototyping; Guided bone regeneration; Selective laser melting; Computer aided design; Custom-made device
• ISSN: 1010-5182; 1878-4119
• DOI: 10.1016/j.jcms.2015.10.020

Abstract Objective Development of new custom-made devices to reconstruct alveolar bone for implantation, and comparison with conventional methods were the goals of this study. Materials and methods Using a computer-aided design technique, three-dimensional images were constructed. From these data, custom-made devices were produced by a selective laser melting method with pure titanium. Clinical trials also have been conducted with 26 participants who needed bone reconstruction before implantation; they were divided into 2 groups with 13 patients each. The first group uses custom-made devices; the other uses commercial titanium meshes that need to bend during operation. Some clinical aspects are evaluated after the trial. Results The custom-made devices can be produced closely by following the data precisely. Devices are fit for bone defect site. Moreover, the operation time of the custom-made group (75.4 ± 11.6 min) was significantly shorter than that of the conventional group (111.9 ± 17.8 min) ( p  < 0.01). Mucosal rupture occurs, without significant difference ( p  = 0.27), in a patient in the custom-made without severe infection (7.7%), and 3 in conventional (23.1%), respectively. The retaining screw is significantly fewer in the custom-made group than commercial mesh group ( p  < 0.01). Conclusion These results indicate that our novel protocol could be simple and safe for providing powerful support for guided bone regeneration.