A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly

NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal bleeding, cardiovascular side effects, and NSAID...

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Bibliographic Details
Published inAging and disease Vol. 9; no. 1; pp. 143 - 150
Main Authors Wongrakpanich, Supakanya, Wongrakpanich, Amaraporn, Melhado, Katie, Rangaswami, Janani
Format Journal Article
LanguageEnglish
Published United States JKL International 01.02.2018
JKL International LLC
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Summary:NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal bleeding, cardiovascular side effects, and NSAID induced nephrotoxicity. As our society ages, it is crucial to have comprehensive knowledge of this class of medication in the elderly population. Therefore, we reviewed the pharmacodynamics and pharmacokinetics, current guidelines for NSAIDs use, adverse effect profile, and drug interaction of NSAIDs and commonly used medications in the elderly.
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ISSN:2152-5250
2152-5250
DOI:10.14336/AD.2017.0306