Establishment and Characterization of Feline Mammary Tumor Patient-Derived Xenograft Model

• Published in: Animals (Basel) Vol. 11; no. 8; p. 2380
• Main Authors: Chuang, Hsiao-Li, Chang, Yi-Chih, Huang, Yi-Ting, Liao, Jiunn-Wang, Kao, Pei-Ling, Chen, Yi-Fei, Lin, Bin-Yin, Lin, Yi-Lo, Chen, Ter-Hsin, Wang, Yu-Chih
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 12.08.2021; MDPI
• Subjects: Cancer therapies; cats; cell line; cell lines; Chemotherapy; feline mammary tumor; immunohistochemistry; Laboratories; liver; lungs; mammary neoplasms (animal); Medical research; Metastasis; microsatellite repeats; patient-derived xenograft; patients; Tumors; xenotransplantation; United States > US; Taiwan

Feline mammary tumor is a relatively commonly diagnosed neoplasm in the cat. Development of new veterinary cancer therapies is limited by the shortage of in vivo models that reproduce tumor microenvironment and metastatic progression. Four feline mammary tumor orthotopic patient-derived xenograft mo...