Dietary Zinc Acts as a Sleep Modulator

While zinc is known to be important for many biological processes in animals at a molecular and physiological level, new evidence indicates that it may also be involved in the regulation of sleep. Recent research has concluded that zinc serum concentration varies with the amount of sleep, while oral...

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Published inInternational journal of molecular sciences Vol. 18; no. 11; p. 2334
Main Authors 裏出 良博, Urade Yoshihiro, Cherasse Yoan
Format Journal Article
LanguageEnglish
Published Switzerland Molecular Diversity Preservation International 05.11.2017
MDPI AG
MDPI
Subjects
Review
Sleep
Zinc
sleep
nutrition
brain
zinc
randomized controlled trial
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Summary:While zinc is known to be important for many biological processes in animals at a molecular and physiological level, new evidence indicates that it may also be involved in the regulation of sleep. Recent research has concluded that zinc serum concentration varies with the amount of sleep, while orally administered zinc increases the amount and the quality of sleep in mice and humans. In this review, we provide an exhaustive study of the literature connecting zinc and sleep, and try to evaluate which molecular mechanism is likely to be involved in this phenomenon. A better understanding should provide critical information not only about the way zinc is related to sleep but also about how sleep itself works and what its real function is.
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ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms18112334