The Anti-Inflammatory and Anti-Oxidant Mechanisms of the Keap1/Nrf2/ARE Signaling Pathway in Chronic Diseases

• Published in: Aging and disease Vol. 10; no. 3; pp. 637 - 651
• Main Authors: Tu, Wenjun, Wang, Hong, Li, Song, Liu, Qiang, Sha, Hong
• Format: Journal Article
• Language: English
• Published: United States JKL International 01.06.2019; JKL International LLC
• Subjects: Anti-inflammatory agents; Antioxidants (Nutrients); B cells; Biochemistry; Biotechnology; Chronic diseases; Free radicals; Genes; Genetic aspects; Homeostasis; Inflammation; Liver; Metabolites; Nervous system diseases; Neurodegenerative diseases; Oxidative stress; Physiological aspects; Review; Transcription (Genetics); China; Oxidative stress; Reactive oxygen species; Keap1/Nrf2/ARE; Anti-oxidant; Anti-inflammatory; Low-level laser irradiation

Oxidative stress is defined as an imbalance between production of free radicals and reactive metabolites or [reactive oxygen species (ROS)] and their elimination by through protective mechanisms, including (antioxidants). This Such imbalance leads to damage of cells and important biomolecules and ce...