Estimating normal lung weight measurement using postmortem CT in forensic cases

• Published in: Legal medicine (Tokyo, Japan) Vol. 29; pp. 77 - 81
• Main Authors: Matoba, Kotaro, Hyodoh, Hideki, Murakami, Manabu, Saito, Atsuko, Matoba, Tomoko, Ishida, Lisa, Fujita, Emi, Yamase, Mayumi, Jin, Shigeki
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.11.2017
• Subjects: Adult; Aged; Aged, 80 and over; Autopsy; Cadaver; Female; Forensic Pathology; Humans; Lung - physiology; Lungs; Male; Middle Aged; Organ Size; Postmortem Changes; Postmortem CT; Tomography, X-Ray Computed; Volumetry; Weight; Young Adult; Lungs; Autopsy; Volumetry; Weight; Postmortem CT
• ISSN: 1344-6223; 1873-4162
• DOI: 10.1016/j.legalmed.2017.10.014

•Normal aerated lung weight was measured in autopsy and compared with postmortem CT.•The lung weight was 284.9 ± 14.8 g in right lung and 249.3 ± 12.9 g in left lung in autopsy.•The postmortem CT estimated lung weight yielded a high correlation coefficient with lung weight in autopsy (R2 = 0.840).•Postmortem CT could be used to estimate lung weight in normal aerated lung. The aim of this study is to estimate the lung weight using postmortem CT in well aerated lung autopsy cases. The correlation coefficients to the lung weight were also evaluated for the cadavers’ height, weight, whole body surface area (WBSA), body mass index, and estimated lung volume. From October 2015 to July 2016, 31 cadavers (male 12, female 19, age 20–98 (mean 66.9) y.o., postmortem interval 0.3–75.0 (5.7) days) were compared as regards body weight, height, whole body surface area (WBSA), body mass index (BMI), lung volume on CT, and total lung volume classified into several CT number categories, with their lung weight in autopsy. The lung weight (mean ± SE) was 284.9 ± 14.8 g in right lung and 249.3 ± 12.9 g in left lung. The %ALV was 79.9 ± 0.9 HU (mean ± standard error (SE)) in both lungs, 80.3 ± 1.3 HU in right lung, and 77.6 ± 2.0 HU in left lung. Using a simple linear regression test, there was no statistically significant correlation between the lung weight and the categories (R2: body height 0.234, weight 0.224, WBSA 0.309, BMI 0.046, lung volume 0.059). The volume for each individual CT density category showed no significant correlation, but the stepwise regression test yielded an excellent correlation coefficient (R2 = 0.840). The well aerated lung weight was 284.9 ± 14.8 g in right lung and 249.3 ± 12.9 g in left lung, and the postmortem CT could estimate the lung weight with high correlation coefficient.