Data on gut metagenomes of the patients with alcoholic dependence syndrome and alcoholic liver cirrhosis

• Published in: Data in brief Vol. 11; no. C; pp. 98 - 102
• Main Authors: Tyakht, Alexander V., Dubinkina, Veronika B., Odintsova, Vera Y., Yarygin, Konstantin S., Kovarsky, Boris A., Pavlenko, Alexander V., Ischenko, Dmitry S., Popenko, Anna S., Alexeev, Dmitry G., Taraskina, Anastasiya Y., Nasyrova, Regina F., Krupitski, Evgeny M., Shalikiani, Nino V., Bakulin, Igor G., Shcherbakov, Petr L., Skorodumova, Lyubov O., Larin, Andrei K., Kostryukova, Elena S., Abdulkhakov, Rustam A., Abdulkhakov, Sayar R., Malanin, Sergey Y., Ismagilova, Ruzilya K., Grigoryeva, Tatiana V., Ilina, Elena N., Govorun, Vadim M.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.04.2017; Elsevier
• Subjects: alcohol abuse; Alcohol dependence syndrome; Alcoholic liver cirrhosis; Alcoholism; Data; digestive system; Dysbiosis; Gut microbiota; intestinal microorganisms; liver cirrhosis; Metagenome; metagenomics; “Shotgun” metagenomics; Gut microbiota; Alcohol dependence syndrome; Alcoholism; “Shotgun” metagenomics; Dysbiosis; Metagenome; Alcoholic liver cirrhosis
• ISSN: 2352-3409; 2352-3409
• DOI: 10.1016/j.dib.2017.01.008

Alcoholism is associated with significant changes in gut microbiota composition. Metagenomic sequencing allows to assess the altered abundance levels of bacterial taxa and genes in a culture-independent way. We collected 99 stool samples from the patients with alcoholic dependence syndrome (n=72) and alcoholic liver cirrhosis (n=27). Each of the samples was surveyed using “shotgun” (whole-genome) sequencing on SOLiD platform. The reads are deposited in the ENA (project ID: PRJEB18041).