Primary spinal chondrosarcoma: radiological manifestations with histopathological correlation in eight patients and literature review

• Published in: Clinical imaging Vol. 37; no. 1; pp. 124 - 133
• Main Authors: Liu, Guobing, Wu, Guangyao, Ghimire, Prasanna, Pang, Haopeng, Zhang, Zaipeng
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2013; Elsevier Limited
• Subjects: Adult; Aged; Bones; Chondrosarcoma; Chondrosarcoma - diagnosis; Computed tomography (CT); Correlation; Cysts; Disease; Female; Hip joint; Humans; Lesions; Literature reviews; Magnetic resonance imaging (MRI); Magnetic Resonance Imaging - methods; Male; Medical imaging; Middle Aged; Moisture content; Patients; Radiation therapy; Radiology; Reproducibility of Results; Sensitivity and Specificity; Spinal Neoplasms - diagnosis; Spine; Spine - diagnostic imaging; Spine - pathology; Statistics as Topic; Tomography, X-Ray Computed - methods; Tumors; X-ray; Young Adult; Germany; Magnetic resonance imaging (MRI); Chondrosarcoma; Computed tomography (CT); X-ray; Spine
• ISSN: 0899-7071; 1873-4499
• DOI: 10.1016/j.clinimag.2012.02.010

Abstract Purpose The aim of this study was to delineate radiological–pathological correlation in primary vertebral chondrosarcoma. Methods Eight histopathologically confirmed cases were analyzed for pathological and radiological characteristics. Results Magnetic resonance images of three conventional and one clear cell cases showed lobulated or irregular masses with line or septa enhancement. Two conventional lesions showed signal intensity of high water content on T2-weighted images, in which aneurismal bone cysts were confirmed. The myxoid lesion showed a relatively diffuse signal and enhancement. Marked masses were found in the two mesenchymal patients, either dumbbell-like or round-like. Conclusion Primary spinal chondrosarcomas have certain radiological findings that may correlate to the pathological subtypes.