Low-fluence rate, long duration photodynamic therapy in glioma mouse model using organic light emitting diode (OLED)
Highlights • We demonstrated the feasibility of low-fluence rate and long duration OLED-PDT in glioma mouse model. • Tumor severity shows statistically significant correlation with survival days. • mPDT in glioma mouse model is promising with a longer survival time. • Maintenance of photosensitizer...
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Published in | Photodiagnosis and photodynamic therapy Vol. 12; no. 3; pp. 504 - 510 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier B.V
01.09.2015
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Subjects | |
Online Access | Get full text |
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Summary: | Highlights • We demonstrated the feasibility of low-fluence rate and long duration OLED-PDT in glioma mouse model. • Tumor severity shows statistically significant correlation with survival days. • mPDT in glioma mouse model is promising with a longer survival time. • Maintenance of photosensitizer fluorescence and oxygenation is critical for PDT. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1572-1000 1873-1597 |
DOI: | 10.1016/j.pdpdt.2015.04.007 |