A Monoclonal Antibody Defining Human B Cell Differentiation Antigen (HLB-1 Antigen)

• Published in: Microbiology and immunology Vol. 27; no. 1; pp. 51 - 64
• Main Authors: Kasai, Kiyoshi, Koshiba, Hirofumi, Ishii, Yoshifumi, Kikuchi, Koukichi
• Format: Journal Article
• Language: English
• Published: Australia Blackwell Publishing Ltd 01.01.1983
• Subjects: Animals; Antibodies, Monoclonal - immunology; Antigens, Differentiation, B-Lymphocyte; Antigens, Surface - immunology; B-Lymphocytes - cytology; B-Lymphocytes - immunology; Bone Marrow - immunology; Cell Differentiation; Cell Line; Epstein-Barr virus; Humans; Hybridomas - immunology; Leukemia - immunology; Lymphoid Tissue - immunology; Lymphoma - immunology; Mice; Mice, Inbred BALB C; Multiple Myeloma - immunology

A new monoclonal antibody specific for human B cell differentiation antigen (HLB‐1) is produced by a hybridoma established by fusion of splenocytes of mice immunized with the Epstein‐Barr virus (EBV)‐transformed peripheral B cell line, RPMI‐8057. This monoclonal, antibody designated anti‐HLB‐1 monoc...