Immunomodulating Hydrogels as Stealth Platform for Drug Delivery Applications

• Published in: Pharmaceutics Vol. 14; no. 10; p. 2244
• Main Authors: Rezaei, Zahra, Yilmaz-Aykut, Dilara, Tourk, Fatima Mumtaza, Bassous, Nicole, Barroso-Zuppa, Margot, Shawl, Asif Iqbal, Ashraf, Syed Salman, Avci, Huseyin, Hassan, Shabir
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.10.2022; MDPI
• Subjects: Antimitotic agents; Antineoplastic agents; Arthritis; Biodegradable materials; biomaterials; Biomedical materials; Cancer therapies; Chemical properties; Colloids; Cytokines; Diabetes; Dosage and administration; Drug delivery systems; Drugs; Fibroblasts; Foreign bodies; foreign body response; Genotype & phenotype; Glucose; Growth factors; Health aspects; Hydrogels; immune modulation; Immunotherapy; Inflammation; Insulin; Nanoparticles; Osteoarthritis; Pharmaceutical research; Regenerative medicine; Review; Tissue engineering; Transplants & implants; Vehicles; United Arab Emirates

Non-targeted persistent immune activation or suppression by different drug delivery platforms can cause adverse and chronic physiological effects including cancer and arthritis. Therefore, non-toxic materials that do not trigger an immunogenic response during delivery are crucial for safe and effect...