Nanoparticles as Drug Delivery Systems: A Review of the Implication of Nanoparticles' Physicochemical Properties on Responses in Biological Systems

In the last four decades, nanotechnology has gained momentum with no sign of slowing down. The application of inventions or products from nanotechnology has revolutionised all aspects of everyday life ranging from medical applications to its impact on the food industry. Nanoparticles have made it po...

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Bibliographic Details
Published inPolymers Vol. 15; no. 7; p. 1596
Main Authors Yusuf, Azeez, Almotairy, Awatif Rashed Z, Henidi, Hanan, Alshehri, Ohoud Y, Aldughaim, Mohammed S
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 23.03.2023
MDPI
Subjects
Analysis
Anticancer properties
Bioavailability
Biocompatibility
Biological effects
Biological properties
Cosmetics
Drug delivery systems
Drugs
Food additives
Food products
Fruit juices
Global economy
Identification and classification
Ingredients
Medicine
Nanomaterials
nanomedicine
Nanoparticles
Nanotechnology
Pathogens
Properties
R&D
Research & development
Review
Strawberries
Tissue engineering
Toothpaste
Toxicity
Vehicles
Zinc oxides
Saudi Arabia
nanotechnology
drug delivery systems
nanomedicine
nanoparticles
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Summary:In the last four decades, nanotechnology has gained momentum with no sign of slowing down. The application of inventions or products from nanotechnology has revolutionised all aspects of everyday life ranging from medical applications to its impact on the food industry. Nanoparticles have made it possible to significantly extend the shelf lives of food product, improve intracellular delivery of hydrophobic drugs and improve the efficacy of specific therapeutics such as anticancer agents. As a consequence, nanotechnology has not only impacted the global standard of living but has also impacted the global economy. In this review, the characteristics of nanoparticles that confers them with suitable and potentially toxic biological effects, as well as their applications in different biological fields and nanoparticle-based drugs and delivery systems in biomedicine including nano-based drugs currently approved by the U.S. Food and Drug Administration (FDA) are discussed. The possible consequence of continuous exposure to nanoparticles due to the increased use of nanotechnology and possible solution is also highlighted.
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ISSN:2073-4360
2073-4360
DOI:10.3390/polym15071596