Myricetin: A comprehensive review on its biological potentials

• Published in: Food science & nutrition Vol. 9; no. 10; pp. 5854 - 5868
• Main Authors: Imran, Muhammad, Saeed, Farhan, Hussain, Ghulam, Imran, Ali, Mehmood, Zaffar, Gondal, Tanweer Aslam, El‐Ghorab, Ahmed, Ahmad, Ishtiaque, Pezzani, Raffaele, Arshad, Muhammad Umair, Bacha, Umar, Shariarti, Mohammad Ali, Rauf, Abdur, Muhammad, Naveed, Shah, Zafar Ali, Zengin, Gokhan, Islam, Saiful
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.10.2021; John Wiley and Sons Inc; Wiley
• Subjects: anticancer; antidiabetic; Antidiabetics; Apoptosis; Bioavailability; Biomedical materials; Cell cycle; Clinical trials; Cytochrome; Diabetes mellitus; Drug dosages; Energy balance; Glycolysis; Immunology; Inflammation; Kinases; Lipids; Myricaceae; Myricetin; Natural products; Oral administration; Osteoclastogenesis; Osteoporosis; Pharmacokinetics; phytochemical; Protein expression; Proteins; Review; Reviews; Serum proteins; Tea; Thyroid cancer; antidiabetic; Myricetin; anticancer; Myricaceae; phytochemical
• ISSN: 2048-7177; 2048-7177
• DOI: 10.1002/fsn3.2513

Myricetin is a critical nutritive component of diet providing immunological protection and beneficial for maintaining good health. It is found in fruits, vegetables, tea, and wine. The families Myricaceae, Polygonaceae, Primulaceae, Pinaceae, and Anacardiaceae are the richest sources of myricetin. Different researchers explored the therapeutic potential of this valuable constituent such as anticancer, antidiabetic, antiobesity, cardiovascular protection, osteoporosis protection, anti‐inflammatory, and hepatoprotective. In addition to these, the compound has been tested for cancer and diabetic mellitus during clinical trials. Health benefits of myricetin are related to its impact on different cell processes, such as apoptosis, glycolysis, cell cycle, energy balance, lipid level, serum protein concentrations, and osteoclastogenesis. This review explored the potential health benefits of myricetin with a specific emphasis on its mechanism of action, considering the most updated and novel findings in the field. Myricetin is a critical nutritive component of diet providing immunological protection and beneficial for maintaining good health.