Bioinformatics Analysis of the Inflammation-Associated lncRNA-mRNA Coexpression Network in Type 2 Diabetes

• Published in: Journal of the renin-angiotensin-aldosterone system Vol. 2023; p. 6072438
• Main Authors: Huang, Linjuan, Xiong, Shengxi, Liu, Hanshuang, Li, Min, Zhang, Ranran, Liu, Yan, Hu, Xiaolei
• Format: Journal Article
• Language: English
• Published: England Hindawi 01.01.2023; Hindawi Limited
• Subjects: Bioinformatics; Biomarkers; Computational Biology; Diabetes; Diabetes Mellitus, Type 2; Endocrine system; Genes; Humans; Inflammation; Lipopolysaccharides; RNA, Long Noncoding; RNA, Messenger; Sodium-Potassium-Exchanging ATPase

Introduction. Diabetes is a chronic inflammatory state, and a key role of lncRNAs in diabetes complications is a new area of research. Methods. In this study, key lncRNAs related to diabetes inflammation were identified by RNA-chip mining and lncRNA-mRNA coexpression network construction and finally...