Enhancement of Pesticide Peak Response in GC-MS in the Presence of Multiple Co-Existing Reference Pesticides

• Published in: Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) Vol. 59; no. 3; pp. 146 - 150
• Main Authors: Kitagawa, Yoko, Yamaguchi, Satoko, Takatori, Satoshi, Hinoshita, Katsuhiko, Kajimura, Keiji, Watanabe, Takaho, Nishiyama, Takayuki, Namikawa, Mikio, Yamamoto, Naomi, Yoshimitsu, Masato, Fukui, Naoki, Ban, Soichiro, Obana, Hirotaka, Maruyama, Ryoko, Akutsu, Kazuhiko, Shinto, Masanori, Kakutani, Naoya, Miyamoto, Iori, Okubo, Yoshitsugu, Yamashita, Koichi, Osakada, Masakazu, Takai, Yasutomo, Nakashima, Ryo
• Format: Journal Article
• Language: English; Japanese
• Published: Japan Japanese Society for Food Hygiene and Safety 25.06.2018; Japan Science and Technology Agency
• Subjects: Calibration; calibration curve; collaboration study; Food Analysis - methods; Food matrix; Gas Chromatography-Mass Spectrometry; GC-MS; Malathion; matrix effect; Pesticide Residues - analysis; Pesticides; Pesticides - analysis; Soybeans; GC-MS; calibration curve; collaboration study; matrix effect
• ISSN: 0015-6426; 1882-1006
• DOI: 10.3358/shokueishi.59.146

We carried out a collaborative study in six laboratories to confirm the universality of the enhancing effect of co-existing reference pesticides on the GC-MS peak response to a target pesticide (malathion, procymidone, or flucythrinate). First, we confirmed the response enhancement of the target pesticides with increasing numbers of co-existing reference pesticides in solution. Then, using diluted green soybean matrix, we analyzed the target pesticides with two types of matrix-matched calibration, containing the target pesticides or 166 other pesticides. In both cases, the response-enhancing effect of co-existing pesticides was confirmed in all laboratories. The enhancement was reduced by addition of green soybean matrix to the sample and calibration solutions. Our results show that it is necessary to estimate the peak response-enhancing effect of co-existing pesticides in the calibration solution to obtain accurate results with GC-MS determination. The enhancing effect could be reduced by addition of food matrix to the sample and calibration solutions.