Executive Functions, Memory, and Social Cognitive Deficits and Recovery in Chronic Alcoholism: A Critical Review to Inform Future Research

• Published in: Alcoholism, clinical and experimental research Vol. 41; no. 8; pp. 1432 - 1443
• Main Authors: Le Berre, Anne‐Pascale, Fama, Rosemary, Sullivan, Edith V.
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.08.2017; Wiley
• Subjects: Abstinence; Alcohol use; Alcoholism; Alcoholism - diagnosis; Alcoholism - epidemiology; Alcoholism - therapy; Biomedical Research - trends; Clinical Implications; Cognition & reasoning; Cognition Disorders - diagnosis; Cognition Disorders - epidemiology; Cognition Disorders - therapy; Cognitive ability; Cognitive Impairment; Cognitive science; Decision making; Drug abuse; Emotions; Executive function; Executive Function - physiology; Forecasting; Humans; Memory; Memory - physiology; Memory Disorders - diagnosis; Memory Disorders - epidemiology; Memory Disorders - therapy; Neuroscience; Psychology; Recovery; Recovery (Medical); Recovery of Function - physiology; Reviews; Social Behavior; Social interactions; Clinical Implications; Cognitive Impairment; Recovery; Alcoholism; Abstinence
• ISSN: 0145-6008; 1530-0277
• DOI: 10.1111/acer.13431

Alcoholism is a complex and dynamic disease, punctuated by periods of abstinence and relapse, and influenced by a multitude of vulnerability factors. Chronic excessive alcohol consumption is associated with cognitive deficits, ranging from mild to severe, in executive functions, memory, and metacognitive abilities, with associated impairment in emotional processes and social cognition. These deficits can compromise efforts in initiating and sustaining abstinence by hampering efficacy of clinical treatment and can obstruct efforts in enabling good decision making success in interpersonal/social interactions, and awareness of cognitive and behavioral dysfunctions. Despite evidence for differences in recovery levels of selective cognitive processes, certain deficits can persist even with prolonged sobriety. Herein is presented a review of alcohol‐related cognitive impairments affecting component processes of executive functioning, memory, and the recently investigated cognitive domains of metamemory, social cognition, and emotional processing; also considered are trajectories of cognitive recovery with abstinence. Finally, in the spirit of critical review, limitations of current knowledge are noted and avenues for new research efforts are proposed that focus on (i) the interaction among emotion–cognition processes and identification of vulnerability factors contributing to the development of emotional and social processing deficits and (ii) the time line of cognitive recovery by tracking alcoholism's dynamic course of sobriety and relapse. Knowledge about the heterochronicity of cognitive recovery in alcoholism has the potential of indicating at which points during recovery intervention may be most beneficial. We review alcohol‐related cognitive impairments affecting component processes of executive functioning, memory, and the recently investigated cognitive domains of metamemory, social cognition, and emotional processing. Also considered are trajectories of cognitive recovery with abstinence. Knowledge about the heterochronicity of cognitive recovery in alcoholism has the potential of indicating at which points during recovery intervention may be most beneficial.