A case of primary central nervous system histiocytic sarcoma

• Published in: Clinical neurology and neurosurgery Vol. 114; no. 7; pp. 1074 - 1076
• Main Authors: Wang, Jing, Li, Tianlang, Chen, Huaihong, Liu, Qiang
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.09.2012; Elsevier; Elsevier Limited
• Subjects: Antigens, CD - metabolism; Antigens, Differentiation, Myelomonocytic - metabolism; Biological and medical sciences; Biopsy; Brain - pathology; Breast cancer; Central nervous system; Central Nervous System Neoplasms - pathology; Central Nervous System Neoplasms - radiotherapy; Chemotherapy; Diagnosis; Diagnosis, Differential; Fatal Outcome; Female; Gait Disorders, Neurologic - etiology; Histiocytic sarcoma; Histiocytic Sarcoma - pathology; Histiocytic Sarcoma - radiotherapy; Humans; Immunohistochemistry; Lymphoma; Magnetic Resonance Imaging; Medical sciences; Middle Aged; Neurology; Neurosurgery; Prognosis; Radiation therapy; S100 Proteins - metabolism; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Prognosis; Diagnosis; Histiocytic sarcoma; Central nervous system; Nervous system diseases; Sarcoma; Surgery; Malignant tumor; Cancer
• ISSN: 0303-8467; 1872-6968
• DOI: 10.1016/j.clineuro.2012.02.009

ND: no data. 1 Introduction Histiocytic sarcoma (HS) is a rare, lymphohematopoietic malignant tumor composed of tumor cells showing morphologic and immunophenotypic features of mature tissue histiocytes, which accounts for less than 1% of non-Hodgkin's lymphoma. Because HS is one kind of lymphoma, radiation therapy and chemotherapy were considered as modalities of choice, however they did not show to improve prognosis.