Dietary Flavonoids as Cancer Chemopreventive Agents: An Updated Review of Human Studies

Over the past few years, interest in health research has increased, making improved health a global goal for 2030. The purpose of such research is to ensure healthy lives and promote wellbeing across individuals of all ages. It has been shown that nutrition plays a key role in the prevention of some...

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Published inAntioxidants Vol. 8; no. 5; p. 137
Main Authors Rodríguez-García, Carmen, Sánchez-Quesada, Cristina, J Gaforio, José
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 18.05.2019
MDPI
Subjects
Antioxidants
Beverages
Breast cancer
cancer
Cardiovascular diseases
Chemopreventive agents
Cocoa
Diabetes mellitus
diet
Dietary intake
Epidemiology
Flavonoids
Fruits
Metabolites
Polyphenols
Population studies
Prostate
Review
Reviews
cancer
diet
flavonoids
antioxidants
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Summary:Over the past few years, interest in health research has increased, making improved health a global goal for 2030. The purpose of such research is to ensure healthy lives and promote wellbeing across individuals of all ages. It has been shown that nutrition plays a key role in the prevention of some chronic diseases such as obesity, cardiovascular disease, diabetes, and cancer. One of the aspects that characterises a healthy diet is a high intake of vegetables and fruits, as both are flavonoid-rich foods. Flavonoids are one of the main subclasses of dietary polyphenols and possess strong antioxidant activity and anti-carcinogenic properties. Moreover, some population-based studies have described a relationship between cancer risk and dietary flavonoid intake. In this context, the goal of this review was to provide an updated evaluation of the association between the risk of different types of cancers and dietary flavonoid intake. We analysed all relevant epidemiological studies from January 2008 to March 2019 using the PUBMED and Web of Science databases. In summary, this review concludes that dietary flavonoid intake is associated with a reduced risk of different types of cancer, such as gastric, breast, prostate, and colorectal cancers.
ISSN:2076-3921
2076-3921
DOI:10.3390/antiox8050137