Unveiling the potential of proteomics in addressing food and feed safety challenges

The food and feed sector in Europe is rapidly evolving to address contemporary challenges, striving for fairer, safer, greener and more sustainable food systems. This includes the exploration of new protein sources for human consumption and animal feed such as protein derived from insects, algae or...

Full description

Saved in:
Bibliographic Details
Published inEFSA journal Vol. 21; no. Suppl 1; pp. e211013 - n/a
Main Authors Perkons, Ingus, Varunjikar, Madhushri Shrikant, Rasinger, Josef Daniel
Format Journal Article
LanguageEnglish
Published Hoboken John Wiley & Sons, Inc 01.11.2023
John Wiley and Sons Inc
Wiley
Subjects
Algae
Allergens
alternative protein sources
Animal feed
Animal protein
Eu‐fora Series 6
Feeds
Food
Food safety
Food sources
Fraud
Genetically altered foods
Identification
Insects
Laboratories
Mass spectrometry
Mass spectroscopy
Novel foods
Pathogens
Plants
processed animal protein
Protein arrays
Protein sources
Proteins
Proteomics
Risk assessment
Safety
Safety research
species identification
Sustainable food systems
tissue identification
Toxicology
Online AccessGet full text

Cover

More Information
Summary:The food and feed sector in Europe is rapidly evolving to address contemporary challenges, striving for fairer, safer, greener and more sustainable food systems. This includes the exploration of new protein sources for human consumption and animal feed such as protein derived from insects, algae or novel plant‐derived proteins, and the re‐evaluation of existing sources like processed animal protein (PAP). To generate reliable data on the diverse array of emerging protein sources for future food and feed safety assessments, a growing demand for the development and implementation of advanced analytical techniques exists. New approach methodologies (NAMs) including, mass spectrometry (MS)‐based proteomics methods have been emerging as valuable techniques which potentially can be implemented in regulatory laboratory settings to complement conventional approaches in this realm. These MS‐driven strategies have already proven their utility in diverse applications, including the detection of prohibited substances in feed, identification of allergens, differentiation of fish species in complex mixtures for fraud detection and the verification of novel foods and alternative protein sources. This EU‐FORA programme was focused on three core objectives namely: (i) the training of the fellow in utilising MS‐based proteomics for food and feed safety analyses, (ii) the involvement of the fellow in the development of standardised operating procedures (SOP) for targeted and non‐targeted proteomic MS‐based workflows for species and tissues specific PAP identification in a national reference laboratory (NRL) and (iii) the transfer and implementation of MS‐based approaches and standardised protocols for PAP analysis at the fellow's home institution. Altogether, this programme facilitates the broadening and diversification of use of MS‐based proteomic methodologies for reinforcing their significance within the domains of food and feed safety research and regulatory science applications.
Bibliography:If you wish to access the declaration of interests of any expert contributing to an EFSA scientific assessment, please contact
Declarations of interest
interestmanagement@efsa.europa.eu
EFSA may include images or other content for which it does not hold copyright. In such cases, EFSA indicates the copyright holder and users should seek permission to reproduce the content from the original source.
This report is funded by EFSA as part of the 2022‐2023 EU‐FORA Fellowship Programme. We would like to thank Dr Kai Lie, representative of the National Reference Laboratory (NRL) for Animal Protein (AP) at the Institute of Marine Research (IMR) in Norway, for his valuable input concerning current PAP detection methods and regulations. Sincere thanks to Prof. Magnus Palmblad from the Leiden University Medical Center (LUMC) in the Netherlands for key support and vital input to all technical aspect of mass spectrometry and proteomics bioinformatics related work. The authors express their gratitude to Dr. Vadims Bartkevics and Dr. Dzintars Zacs of the Institute for Food Safety, Animal Health and Environment (BIOR) for their support throughout the programme. Their provision of technical resources and essential laboratory materials played a pivotal role in facilitating the proteomics analysis at BIOR.
Acknowledgements
.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Acknowledgements This report is funded by EFSA as part of the 2022‐2023 EU‐FORA Fellowship Programme. We would like to thank Dr Kai Lie, representative of the National Reference Laboratory (NRL) for Animal Protein (AP) at the Institute of Marine Research (IMR) in Norway, for his valuable input concerning current PAP detection methods and regulations. Sincere thanks to Prof. Magnus Palmblad from the Leiden University Medical Center (LUMC) in the Netherlands for key support and vital input to all technical aspect of mass spectrometry and proteomics bioinformatics related work. The authors express their gratitude to Dr. Vadims Bartkevics and Dr. Dzintars Zacs of the Institute for Food Safety, Animal Health and Environment (BIOR) for their support throughout the programme. Their provision of technical resources and essential laboratory materials played a pivotal role in facilitating the proteomics analysis at BIOR.
Approved: 15 September 2023
Declarations of interest If you wish to access the declaration of interests of any expert contributing to an EFSA scientific assessment, please contact interestmanagement@efsa.europa.eu.
ISSN:1831-4732
1831-4732
DOI:10.2903/j.efsa.2023.e211013