Dental management of patients at risk of osteochemonecrosis of the jaws: a critical review
Osteonecrosis of the jaw bones is a complication of bisphosphonate (BP) drug usage characterised by trans‐mucosal exposure of necrotic bone, often followed by infection and pain. Osteonecrosis is observed in cancer patients on high‐potency intravenous BP more frequently than in osteoporotic individu...
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Published in | Oral diseases Vol. 15; no. 8; pp. 527 - 537 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Publishing Ltd
01.11.2009
Wiley |
Subjects | |
Online Access | Get full text |
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Summary: | Osteonecrosis of the jaw bones is a complication of bisphosphonate (BP) drug usage characterised by trans‐mucosal exposure of necrotic bone, often followed by infection and pain. Osteonecrosis is observed in cancer patients on high‐potency intravenous BP more frequently than in osteoporotic individuals using low‐potency oral BP. The management of osteonecrosis caused by BP is often unsatisfactory and control of risk factors is considered the most effective means of prevention. Surgical manipulation and dental infection of the jawbone are the major risk factors, hence it is suggested that careful management of oral health and relevant dental procedures may decrease the risk of osteonecrosis in individuals on BP. Recommendations for dentists and oral surgeons have been suggested by different groups of clinicians but they are often controversial and there is no clear evidence for their efficacy in reducing the likelihood of osteonecrosis development. This report critically reviews current dental recommendations for individuals using BP with the aim of helping the reader to transfer them into practice as part of pragmatic and non‐detrimental clinical decisions making. |
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Bibliography: | istex:F88DE86B8B93C48E210D899A31E126398C2F4D3F ArticleID:ODI1581 ark:/67375/WNG-89TTFB7D-9 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
ISSN: | 1354-523X 1601-0825 |
DOI: | 10.1111/j.1601-0825.2009.01581.x |