The Roles of Extracellular Vesicles in the Progression of Renal Cell Carcinoma and Their Potential for Future Clinical Application

• Published in: Nanomaterials (Basel, Switzerland) Vol. 13; no. 10; p. 1611
• Main Authors: Takeda, Masashi, Akamatsu, Shusuke, Kita, Yuki, Goto, Takayuki, Kobayashi, Takashi
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 11.05.2023; MDPI
• Subjects: Angiogenesis; biomarker; Biosynthesis; Cancer; cancer progression; Carcinoma, Renal cell; Cells; Development and progression; Drug resistance; Epithelial cells; Epithelium; extracellular vesicle; Extracellular vesicles; Heat shock proteins; Hypoxia; Immune system; Immunomodulation; Kidney cancer; Lipid bilayers; Lipids; Medical research; Membrane lipids; Metastases; Metastasis; MicroRNAs; Microscopy; Nanoparticles; Proteomics; Renal cell carcinoma; Review; therapeutics; Tumor necrosis factor-TNF; Vesicles; renal cell carcinoma; therapeutics; cancer progression; biomarker; extracellular vesicle

Renal cell carcinoma (RCC) is the most common type of kidney cancer and is thought to originate from renal tubular epithelial cells. Extracellular vesicles (EVs) are nanosized lipid bilayer vesicles that are secreted into extracellular spaces by nearly all cell types, including cancer cells and non-...