Bioactive compounds: Definition and assessment of activity

• Published in: Nutrition (Burbank, Los Angeles County, Calif.) Vol. 25; no. 11; pp. 1202 - 1205
• Main Authors: Biesalski, Hans-Konrad, Dragsted, Lars Ove, Elmadfa, Ibrahim, Grossklaus, Rolf, Müller, Michael, Schrenk, Dieter, Walter, Paul, Weber, Peter
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.11.2009; Elsevier; Elsevier Limited
• Subjects: analysis; Bioactive compounds; Bioactive constituents; bioactive properties; Bioavailability; Biological and medical sciences; Biomarker; Biomarkers; Biomarkers - analysis; Cardiovascular disease; Chronic illnesses; Consensus; Dietary Supplements; dosage; dose response; Feeding. Feeding behavior; food composition; Fundamental and applied biological sciences. Psychology; Gastroenterology and Hepatology; Health effect; health foods; health status; human health; Humans; Intake; Mutation; Nutraceuticals; nutrients; Nutrition; Nutritional Sciences; Phytochemicals; risk factors; risk reduction; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Xenobiotics; Biomarker; Phytochemicals; Intake; Health effect; Bioavailability; Xenobiotics; Bioactive constituents; Nutraceuticals; Health; Biological marker; Vertebrata; Mammalia; Xenobiotic
• ISSN: 0899-9007; 1873-1244; 1873-1244
• DOI: 10.1016/j.nut.2009.04.023

Biomarkers and their role in evaluating efficacy and safety were the topic of the 23rd Hohenheim Consensus Meeting at the University of Hohenheim in Stuttgart. Scientists who had published and reviewed scientific and regulatory papers on the topic were invited, among them basic researchers, toxicologists, clinicians, and nutritionists. The participants were presented with 11 questions (in bold font), which were discussed and answered (in italic font) at the workshop, with the aim of summarizing the current state of knowledge on the subject. The explicatory text accompanying the short answers was produced and agreed on after the conference and was backed up by corresponding references.