Long-range hypoxia signaling in NAFLD

A recent study describes a role for hypoxic signaling in the small intestine in the etiology of nonalcoholic fatty liver disease (NAFLD) and suggests that HIF-2α inhibitors may be an effective option for the treatment of this disease.

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Bibliographic Details
Published inNature medicine Vol. 23; no. 11; pp. 1251 - 1252
Main Authors LaGory, Edward L, Giaccia, Amato J
Format Journal Article
LanguageEnglish
Published New York Nature Publishing Group US 01.11.2017
Nature Publishing Group
Subjects
631/443/319/1642
692/699/1503/1607/2750
Analysis
Anoxia
Biomedicine
Body mass index
Cancer Research
Care and treatment
Diagnosis
Diet
Fatty acids
Health aspects
Humans
Hypoxia
Infectious Diseases
Insulin resistance
Lipids
Liver diseases
Metabolic Diseases
Metabolic syndrome
Molecular Medicine
Neurosciences
news-and-views
Non-alcoholic Fatty Liver Disease
Obesity
Radiation
Signal Transduction
Signaling
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Summary:A recent study describes a role for hypoxic signaling in the small intestine in the etiology of nonalcoholic fatty liver disease (NAFLD) and suggests that HIF-2α inhibitors may be an effective option for the treatment of this disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Commentary-1
ISSN:1078-8956
1546-170X
DOI:10.1038/nm.4436