A putative corticosteroid hormone in Pacific lamprey, Entosphenus tridentatus

• Published in: General and comparative endocrinology Vol. 212; pp. 178 - 184
• Main Authors: Rai, Satbir, Szeitz, András, Roberts, Brent W, Christie, Quill, Didier, Wesley, Eom, Junho, Yun, Sang-Seon, Close, David A
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2015
• Subjects: 11-Deoxycortisol; Adrenocorticotropic Hormone - administration & dosage; Agnathan; Animals; Corticotropin-Releasing Hormone - administration & dosage; Cortodoxone - metabolism; Endocrinology & Metabolism; Entosphenus tridentatus; Glucocorticoid; Hypothalamo-Hypophyseal System - drug effects; Hypothalamo-Hypophyseal System - metabolism; Lampreys - metabolism; Petromyzontidae; Pituitary-Adrenal System - drug effects; Pituitary-Adrenal System - metabolism; Stress; Stress response; Stress, Physiological; I, Pacific; HPI; hypothalamic–pituitary–interrenal; total ion current; ultra high performance liquid chromatography–tandem mass spectrometry; multiple reaction monitoring; hypothalamic–pituitary–adrenal; ACTH; MRM; 11-Deoxycortisol; Agnathan; ultra high performance liquid chromatography; adrenocorticotropic hormone; Glucocorticoid; Stress; corticotropin releasing hormone; TIC; HPA; CRH; UHPLC; Stress response; UHPLC/MS/MS
• ISSN: 0016-6480; 1095-6840
• DOI: 10.1016/j.ygcen.2014.06.019

Highlights • 11-Deoxycortisol is present in Pacific lamprey plasma. • 11-Deoxycortisol levels increase 30 min after exposure to stress. • 11-Deoxycortisol levels increase after injections of sea lamprey CRH peptide. • Sea lamprey ACTHs do not display any stimulatory effects on 11-deoxycrotisol levels.