Parthenogenetic activation decreases the polyphosphoinositide content of frog eggs

• Published in: FEBS letters Vol. 187; no. 1; pp. 61 - 64
• Main Authors: Le Peuch, C.J., Picard, A., Dorée, M.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 22.07.1985; Elsevier
• Subjects: Animals; Biological and medical sciences; Early stages. Segmentation. Gastrulation. Neurulation; Embryology: invertebrates and vertebrates. Teratology; Female; Fertilization; Fundamental and applied biological sciences. Psychology; Metaphase; Oocytes - drug effects; Oocytes - metabolism; Parthenogenesis; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols - metabolism; Polyphosphoinositide Phospholipase C activation Exocytosis Xenopus egg Parthenogenetic activation; PolyphosphoinositidePhospholipaseCactivationExocytosisXenopuseggParthenogeneticactivation; Progesterone - pharmacology; Type C Phospholipases - metabolism; Xenopus; Polyphosphoinositide Phospholipase C activation Exocytosis Xenopus egg Parthenogenetic activation; Parthenogenesis; Amphibia; Vertebrata; Salientia; Metabolism; Frog
• ISSN: 0014-5793; 1873-3468
• DOI: 10.1016/0014-5793(85)81214-X

Polyphosphoinositides were quantified in metaphase II-arrested eggs of the amphibian Xenopus laevis, and 8–10 min later in eggs activated by pricking. The content of phosphatidylinositol 4,5-biphosphate (PIP 2) was remarkably high in metaphase II-arrested eggs with respect to that of phosphatidylinositol 4-phosphate (PIP). It was found to drop dramatically at activation. In contrast PIP content did not change significantly.