Development of Proximal Calciphylaxis with Penile Involvement after Parathyroidectomy in a Patient on Hemodialysis

Elevated parathyroid hormone (PTH) levels and hyperphosphatemia are thought to be associated with the development of calciphylaxis. We report a patient on hemodialysis who developed proximal calciphylaxis with consistently low PTH levels after parathyroidectomy. A 31-year-old man was admitted to our...

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Published inInternal Medicine Vol. 43; no. 1; pp. 63 - 68
Main Authors OIKAWA, Shigeru, OSAJIMA, Akihiko, TAMURA, Masahito, MURATA, Kougi, YASUDA, Hiroshi, ANAI, Hirofumi, KABASHIMA, Narutoshi, MATSUSHIMA, Yoshiyuki, NAKAMOTO, Masahiko, NAKASHIMA, Yasuhide
Format Journal Article
LanguageEnglish
Published Tokyo The Japanese Society of Internal Medicine 2004
Japanese Society of Internal Medicine
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Summary:Elevated parathyroid hormone (PTH) levels and hyperphosphatemia are thought to be associated with the development of calciphylaxis. We report a patient on hemodialysis who developed proximal calciphylaxis with consistently low PTH levels after parathyroidectomy. A 31-year-old man was admitted to our hospital because of abdominal skin ulcerations. Calciphylaxis spread to the penis, and simultaneous progressive lung calcification was evident on chest X-ray, suggestive of pulmonary calciphylaxis on 99mTc-methylene disphosphonate scintigraphy. The patient died of respiratory failure despite intensive treatment including hyperbaric oxygen therapy. This is the first report of a patient on hemodialysis who developed calciphylaxis involving the penis after parathyroidectomy.
Bibliography:ObjectType-Case Study-2
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ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.43.63