Leiomyosarcoma of the spermatic cord: a rare paratesticular neoplasm case report

• Published in: World journal of surgical oncology Vol. 20; no. 1; p. 94
• Main Authors: Ahmed, Farah, Aslam, Asadullah, Tanveer, Yousaf, Jaffry, Syed
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 25.03.2022; BioMed Central; BMC
• Subjects: Adults; Aged; Biomarkers; Calcification; Case Report; Chemotherapy; Cough; Diabetes mellitus; Diagnosis; Disease; Dissection; Genital Neoplasms, Male - diagnosis; Genital Neoplasms, Male - pathology; Genital Neoplasms, Male - surgery; Genitourinary tract; Hernias; Histopathology; Humans; Leiomyosarcoma; Leiomyosarcoma - pathology; Leiomyosarcoma - surgery; Lymphatic system; Male; Mesenchyme; Metastasis; Muscles; Neoplasia; Paratesticular neoplasm; Radiation therapy; Risk factors; Sarcoma; Scrotal mass; Smooth muscle; Soft Tissue Neoplasms - pathology; Soft tissues; Spermatic cord; Spermatic Cord - pathology; Spermatic Cord - surgery; Spermatic cord leiomyosarcoma; Testicular cancer; Thalassemia; Trauma; Tumor markers; Tumors; Ultrasonic imaging; Ultrasonography; Urology; Ireland; Paratesticular neoplasm; Case report; Scrotal mass; Spermatic cord leiomyosarcoma
• ISSN: 1477-7819; 1477-7819
• DOI: 10.1186/s12957-022-02539-9

Primary soft tissue sarcomas contribute to only 2% of all malignancies arising from the male genitourinary tract. Leiomyosarcoma (LMS) is a malignant soft tissue neoplasm which originates from the mesenchyme and has a characteristic smooth muscle differentiation. Usually, it presents as a painless, firm, slow-growing unilateral scrotal mass. Investigations include imaging, tumor markers, and histopathology. A 65-year-old gentleman known diabetic and beta-thalassemic trait was referred to the Urology OPD at Letterkenny University Hospital. His presenting complaint was a left groin lump that appeared 1 year ago and was growing larger in size gradually. According to the patient, his lump was slightly painful (localized) initially that later became painless. He did not report any testicular trauma/infection or UTI. There was no significant history of malignancies running through his family. Clinical examination revealed a soft and lax abdomen, normal testes. There was a non-tender 2cm x 2cm well-circumscribed, mobile, firm to cystic irreducible left inguinoscrotal mass and appeared to be attached to the spermatic cord. Cough impulse was indiscernible. Ultrasound left groin showed 1.8 cm transverse x 1.4 cm AP x 1.9 cm sagittal) well-circumscribed ovoid nodular subcutaneous lesion present in the upper left inguinal area just lateral to the left pubic tubercle that appeared solid with heterogeneous internal echotexture and no internal calcification. Some internal vascularity is demonstrated with color Doppler assessment. Because of its rareness, LMS represents a management conundrum. There is no standard protocol for treatment. We present a case and discuss the available evidence from the literature to date to help identify LMS of the spermatic cord that is highly unusual.