Catecholamine-secreting neuroblastoma in a 4-month-old infant: perioperative management

Abstract Preoperative alpha- and beta-adrenergic receptor block with phenoxybenzamine and labetalol, the intraoperative course of a 4-month-old infant with neuroblastoma and elevated catecholamines causing sweating, hypertension, and tachycardia, are presented. We recommend determination of catechol...

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Bibliographic Details
Published inJournal of clinical anesthesia Vol. 21; no. 1; pp. 54 - 56
Main Authors Hernandez, Michael R., MD, Shamberger, Robert C., MD, Seefelder, Christian, MD
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 01.02.2009
Elsevier
Elsevier Limited
Subjects
Adrenergic alpha-Antagonists - therapeutic use
Adrenergic beta-Antagonists - therapeutic use
Age: infant
Anesthesia
Anesthesia & Perioperative Care
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Anesthesia: general
Biological and medical sciences
Blood pressure
Cardiac arrhythmia
Catecholamines - secretion
Dopamine
Female
Humans
Hypertension
Hypertension - etiology
Infant
Labetalol - therapeutic use
Medical sciences
Neuroblastoma - physiopathology
Neuroblastoma - secretion
Neuroblastoma - surgery
Pain Medicine
Pathology: neuroblastoma
Perioperative Care - methods
Pharmacology: phenoxybenzamine
Phenoxybenzamine - therapeutic use
Postoperative period
Surgery
Sweating
Tachycardia - etiology
Pathology: neuroblastoma
Pharmacology: phenoxybenzamine
Anesthesia: general
Age: infant
Human
Nervous system diseases
Vasodilator agent
α1-Adrenergic receptor
General anesthesia
Infant
Malignant tumor
Neuroblastoma
Phenoxybenzamine
Anatomic pathology
Alpha blocking agent
Clinical management
Antihypertensive agent
Antagonist
Autonomic neuropathy
Cancer
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Summary:Abstract Preoperative alpha- and beta-adrenergic receptor block with phenoxybenzamine and labetalol, the intraoperative course of a 4-month-old infant with neuroblastoma and elevated catecholamines causing sweating, hypertension, and tachycardia, are presented. We recommend determination of catecholamine levels and pretreatment with alpha-adrenergic and–if needed–beta-adrenergic receptor antagonists in infants with neuroblastoma and hypertension, tachycardia, or sweating.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:0952-8180
1873-4529
DOI:10.1016/j.jclinane.2008.06.021