High mitochondrial mass is associated with reconstitution capacity and quiescence of hematopoietic stem cells

•HSCs can be separated based on high or low mitochondrial mass.•Higher mitochondrial mass is associated with quiescence and greater reconstitution capacity of HSCs. [Display omitted]

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Bibliographic Details
Published inBlood advances Vol. 3; no. 15; pp. 2323 - 2327
Main Authors Takihara, Yuji, Nakamura-Ishizu, Ayako, Tan, Darren Qiancheng, Fukuda, Masahiro, Matsumura, Takayoshi, Endoh, Mitsuhiro, Arima, Yuichiro, Chin, Desmond Wai Loon, Umemoto, Terumasa, Hashimoto, Michihiro, Mizuno, Hidenobu, Suda, Toshio
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 13.08.2019
American Society of Hematology
Elsevier
Subjects
Stimulus Report
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Summary:•HSCs can be separated based on high or low mitochondrial mass.•Higher mitochondrial mass is associated with quiescence and greater reconstitution capacity of HSCs. [Display omitted]
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:2473-9529
2473-9537
DOI:10.1182/bloodadvances.2019032169