VIRULIGN: fast codon-correct alignment and annotation of viral genomes

Abstract Summary Virus sequence data are an essential resource for reconstructing spatiotemporal dynamics of viral spread as well as to inform treatment and prevention strategies. However, the potential benefit of these applications critically depends on accurate and correctly annotated alignments o...

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Bibliographic Details
Published inBioinformatics Vol. 35; no. 10; pp. 1763 - 1765
Main Authors Libin, Pieter J K, Deforche, Koen, Abecasis, Ana B, Theys, Kristof
Format Journal Article
LanguageEnglish
Published England Oxford University Press 15.05.2019
Subjects
Applications Notes
Codon
Genome, Viral
Software
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Summary:Abstract Summary Virus sequence data are an essential resource for reconstructing spatiotemporal dynamics of viral spread as well as to inform treatment and prevention strategies. However, the potential benefit of these applications critically depends on accurate and correctly annotated alignments of genetically heterogeneous data. VIRULIGN was built for fast codon-correct alignments of large datasets, with standardized and formalized genome annotation and various alignment export formats. Availability and implementation VIRULIGN is freely available at https://github.com/rega-cev/virulign as an open source software project. Supplementary information Supplementary data is available at Bioinformatics online.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
USDOE Office of Nuclear Energy (NE), Nuclear Fuel Cycle and Supply Chain
GHTM-UID/Multi/04413/2013; PTDC/DTP-EPI/7066/2014
ISSN:1367-4803
1460-2059
1367-4811
DOI:10.1093/bioinformatics/bty851