Defining recurrent implantation failure: a profusion of confusion or simply an illusion?

Recurrent implantation failure (RIF) is a poorly defined clinical scenario marked by failure to achieve pregnancy after multiple embryo transfers. The causes and definitions of implantation failure are heterogeneous, posing limitations on study design as well as the interpretation and application of...

Full description

Saved in:
Bibliographic Details
Published inFertility and sterility Vol. 116; no. 6; pp. 1432 - 1435
Main Authors Garneau, Audrey S., Young, Steven L.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.12.2021
Subjects
definition
embryo implantation
Embryo Implantation - physiology
Embryo Transfer - methods
Embryo Transfer - trends
Endometrium - physiology
Female
Fertilization in Vitro - methods
Fertilization in Vitro - trends
Humans
Pregnancy
Pregnancy Rate - trends
Recurrence
recurrent implantation failure
Treatment Failure
recurrent implantation failure
definition
ART
embryo implantation
Online AccessGet full text

Cover

More Information
Summary:Recurrent implantation failure (RIF) is a poorly defined clinical scenario marked by failure to achieve pregnancy after multiple embryo transfers. The causes and definitions of implantation failure are heterogeneous, posing limitations on study design as well as the interpretation and application of findings. Recent studies suggest a novel, personalized approach to defining RIF. Here, we review the implantation physiology and definitions of the implantation rate, failure, and RIF.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-2
ISSN:0015-0282
1556-5653
DOI:10.1016/j.fertnstert.2021.10.023