Effectiveness of meningococcal serogroup C vaccine programmes

• Published in: Vaccine Vol. 31; no. 41; pp. 4477 - 4486
• Main Authors: Borrow, Ray, Abad, Raquel, Trotter, Caroline, van der Klis, Fiona R.M, Vazquez, Julio A
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 23.09.2013; Elsevier; Elsevier Limited
• Subjects: Adolescence; Age; Allergy and Immunology; Antibodies, Bacterial - blood; Applied microbiology; Babies; Bacterial infections; Bacteriology; Biological and medical sciences; Children; Diphtheria; Fundamental and applied biological sciences. Psychology; Humans; Immunization; Immunologic memory; Licenses; Meningitis; Meningitis, Meningococcal - immunology; Meningitis, Meningococcal - microbiology; Meningitis, Meningococcal - prevention & control; Meningococcal serogroup C vaccine; Meningococcal Vaccines - administration & dosage; Meningococcal Vaccines - immunology; Microbiology; Miscellaneous; Monovalent glycoconjugate vaccine; Neisseria meningitidis; Neisseria meningitidis, Serogroup C - immunology; Population; Proteins; Teenagers; Tetanus; Treatment Outcome; Vaccination - methods; Vaccine effectiveness; Vaccines; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); Canada; United States > US; Europe; Monovalent glycoconjugate vaccine; Children; Meningococcal serogroup C vaccine; Immunologic memory; Vaccine effectiveness; Human; Neisseriaceae; Neisseria meningitidis; Vaccine; Glycoconjugate; Bacteria; Micrococcales; Child
• ISSN: 0264-410X; 1873-2518
• DOI: 10.1016/j.vaccine.2013.07.083

Highlights • Successful glycoconjugate vaccination programmes have reduced the incidence of Meningococcal C (MenC). • Risk of MenC incidence increasing if immunization programmes are not maintained. • Regional differences in vaccination programmes may influence herd protection against MenC. • Adolescence booster vaccinations may be required to maintain herd protection.