Myeloma-associated Systemic Amyloidosis with an Extensive Cutaneous Involvement

Histopathological examination of the skin biopsy showed an eosinophilic homogenous material in dermis on hematoxylin-eosin staining [Figure 2]a. The dermal deposits stained strongly with Congo red [Figure 2]b and exhibited green birefringence when viewed under polarized light. On bone marrow biopsy,...

Full description

Saved in:
Bibliographic Details
Published inIndian journal of dermatology Vol. 62; no. 4; pp. 428 - 429
Main Authors Aggarwal, Parul, Aggarwal, Kamal, Kaur, Sarabjit, Jain, Vijay Kumar
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.07.2017
Medknow Publications & Media Pvt. Ltd
Medknow Publications & Media Pvt Ltd
Wolters Kluwer Medknow Publications
Subjects
Amyloidosis
Correspondences
Dermatology
Multiple myeloma
Proteins
Stains & staining
Urine
Online AccessGet full text

Cover

More Information
Summary:Histopathological examination of the skin biopsy showed an eosinophilic homogenous material in dermis on hematoxylin-eosin staining [Figure 2]a. The dermal deposits stained strongly with Congo red [Figure 2]b and exhibited green birefringence when viewed under polarized light. On bone marrow biopsy, about 60% of total nucleated cells comprised mature and immature plasma cells. [...]the third differential would be the rare variant of localized cutaneous amyloidosis - nodular or tumefactive form.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0019-5154
1998-3611
DOI:10.4103/ijd.IJD_358_16