Twin tubal pregnancy: a rising complication?

• Published in: Fertility and sterility Vol. 94; no. 5; pp. 1910.e13 - 1910.e16
• Main Authors: Svirsky, Ran, M.D, Maymon, Ron, M.D, Vaknin, Zvi, M.D, Mendlovic, Sonia, M.D, Weissman, Ariel, M.D, Halperin, Reuvit, M.D., Ph.D, Herman, Arie, M.D, Pansky, Moti, M.D
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2010
• Subjects: Adult; Female; Humans; Incidence; Internal Medicine; Obstetrics and Gynecology; Pregnancy; Pregnancy Complications - diagnosis; Pregnancy Complications - epidemiology; Pregnancy, Multiple - statistics & numerical data; Pregnancy, Tubal - diagnosis; Pregnancy, Tubal - epidemiology; Reproductive Techniques, Assisted; treatment; tubal pregnancies; Twin; Twins; ultrasound; treatment; tubal pregnancies; incidence; ultrasound; Twin
• ISSN: 0015-0282; 1556-5653
• DOI: 10.1016/j.fertnstert.2010.03.017

Objective To present four cases of twin tubal pregnancies and discuss possible etiologies. Twin tubal pregnancies are a rare event, with incidence rates estimated as 1 out of 725–1,580 of tubal pregnancies. Design Case series. Setting Department of obstetrics and gynecology at a tertiary health care facility. Patient(s) All women with twin tubal pregnancy diagnosed and treated in the department during the years 2007–2009, according to electronic files and histologic reports. Intervention(s) None. Main Outcome Measure(s) Artificial reproductive technique preceding twin tubal pregnancies Result(s) We diagnosed four twin pregnancies of 163 tubal pregnancies, an incidence of 2.4%. Of the four cases, two conceived after gonadotropin stimulation and intrauterine insemination. The third conceived following in vitro fertilization and intracytoplasmic sperm injection. The fourth was a spontaneous conception diagnosed as monochorial monoamniotic twin tubal pregnancy. Conclusion(s) Twin tubal pregnancies may not be as rare as previously thought. Three of the four cases indentified during a 2-year period followed artificial reproductive technique. We hope that this report will promote the study of the epidemiology of this event, improve diagnosis, and encourage the development of treatment modalities.