Microbiota Changes Due to Grape Seed Extract Diet Improved Intestinal Homeostasis and Decreased Fatness in Parental Broiler Hens

• Published in: Microorganisms (Basel) Vol. 8; no. 8; p. 1141
• Main Authors: Grandhaye, Jeremy, Douard, Veronique, Rodriguez-Mateos, Ana, Xu, Yifan, Cheok, Alex, Riva, Antonella, Guabiraba, Rodrigo, Zemb, Olivier, Philippe, Catherine, Monnoye, Magali, Staub, Christophe, Venturi, Eric, Barbe, Alix, Ramé, Christelle, Dupont, Joelle, Froment, Pascal
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 28.07.2020; MDPI
• Subjects: adipose tissue; Age; Animal biology; Animals; Bacteria; Body composition; broiler; Broilers (Poultry); Chromatography; Diet; Dietary supplements; Eggs; Feeds; Fertility; Flavonoids; Food and Nutrition; grape seed; Grapes; Health aspects; Homeostasis; Inflammation; Intestine; Intestines; Life Sciences; Materia medica, Vegetable; Metabolism; Metabolites; Microbiota; Microbiota (Symbiotic organisms); Parameter modification; Phenolic compounds; Phenols; Physiological aspects; Plant extracts; Plasma; Poultry; Probiotics; Relative abundance; Seeds; Ultrasonic imaging; France; Microbiota; Grape seed; Adipose tissue; Broiler
• ISSN: 2076-2607; 2076-2607
• DOI: 10.3390/microorganisms8081141

In poultry, the selection of broilers for growth performance has induced a deterioration in the health of the parental hens associated with poor reproductive efficiency. To improve these parameters, we administered to laying parental broiler hens a regular diet supplemented or not (Control) with a moderate (1%) or a high level (2%) of grape seed extract (GSE). The 1% GSE diet was administered from a young age (from 4 to 40 weeks of age) and the high level of 2% GSE was administered only during a 2-week period (from 38 to 40 weeks of age) in the laying period. The analysis of 40-week-old hens showed that 2% GSE displayed a reduction in the fat tissue and an improvement in fertility with heavier and more resistant eggs. Seven monomer phenolic metabolites of GSE were significantly measured in the plasma of the 2% GSE hens. GSE supplementation increased the relative abundance of the following bacteria populations: Bifidobacteriaceae, Lactobacilliaceae and Lachnospiraceae. In conclusion, a supplementation period of only 2 weeks with 2% GSE is sufficient to improve the metabolic and laying parameters of breeder hens through a modification in the microbiota.