Condensins and the evolution of torsion-mediated genome organization

Highlights • Torsional stress on DNA contributes to genome organization in bacteria and eukaryotes. • The basal levels of genome organization are different between bacteria and eukaryotes. • Eukaryotic condensins might have evolved to organize nucleosome fibers in mitosis.

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Bibliographic Details
Published inTrends in cell biology Vol. 24; no. 12; pp. 727 - 733
Main Author Hirano, Tatsuya
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.12.2014
Subjects
Adenosine Triphosphatases - genetics
Bacteria - genetics
chromosomes
Chromosomes - genetics
condensins
DNA - genetics
DNA supercoiling
DNA-Binding Proteins - genetics
Eukaryota - genetics
evolution
Evolution, Molecular
Genome
genomes
Humans
Multiprotein Complexes - genetics
nucleosomes
Nucleosomes - genetics
Pathology
DNA supercoiling
genomes
evolution
nucleosomes
condensins
chromosomes
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Summary:Highlights • Torsional stress on DNA contributes to genome organization in bacteria and eukaryotes. • The basal levels of genome organization are different between bacteria and eukaryotes. • Eukaryotic condensins might have evolved to organize nucleosome fibers in mitosis.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0962-8924
1879-3088
DOI:10.1016/j.tcb.2014.06.007