The Management of Refractory Status Epilepticus: An Update

Refractory status epilepticus (RSE) is an important and serious clinical problem that typically requires prolonged and high‐level intensive care, and is often associated with poor outcome. This review addresses some of the current issues concerning the management of RSE, including recent definitions...

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Bibliographic Details
Published inEpilepsia (Copenhagen) Vol. 47; no. s1; pp. 35 - 40
Main Author Lowenstein, Daniel H.
Format Journal Article
LanguageEnglish
Published Malden, USA Blackwell Publishing Inc 01.10.2006
Subjects
Anesthetics - administration & dosage
Anesthetics - therapeutic use
Anticonvulsants - therapeutic use
Antiepileptic drugs
Clinical Protocols
Decision Trees
Drug Administration Schedule
Drug Resistance
Fructose - analogs & derivatives
Fructose - therapeutic use
Health Care Surveys - statistics & numerical data
Humans
Practice Patterns, Physicians' - statistics & numerical data
Seizures
Status epilepticus
Status Epilepticus - diagnosis
Status Epilepticus - drug therapy
Terminology as Topic
Treatment Outcome
Valproic Acid - therapeutic use
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Summary:Refractory status epilepticus (RSE) is an important and serious clinical problem that typically requires prolonged and high‐level intensive care, and is often associated with poor outcome. This review addresses some of the current issues concerning the management of RSE, including recent definitions used for clinical studies, epidemiology, clinical course, and outcome. Current approaches to treatment, including the now relatively standard use of intravenous anesthetic agents, as well as emerging therapies utilizing drugs such as valproate and topiramate, are discussed as well.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0013-9580
1528-1167
DOI:10.1111/j.1528-1167.2006.00658.x