Continuous Evolution Profiles for Electronic-Tongue-Based Analysis

• Published in: Angewandte Chemie (International ed.) Vol. 51; no. 41; pp. 10394 - 10398
• Main Authors: Hou, Yanxia, Genua, Maria, Tada Batista, Dayane, Calemczuk, Roberto, Buhot, Arnaud, Fornarelli, Pauline, Koubachi, Jamal, Bonnaffé, David, Saesen, Els, Laguri, Cédric, Lortat-Jacob, Hugues, Livache, Thierry
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 08.10.2012; WILEY‐VCH Verlag; Wiley; Wiley Subscription Services, Inc; Wiley-VCH Verlag
• Edition: International ed. in English
• Subjects: Analytical chemistry; Arrays; Biochemistry, Molecular Biology; Biosensing Techniques; biosensors; Chemical Sciences; Chemistry; Chemistry, Multidisciplinary; Chemokine CXCL12; Chemokine CXCL12 - chemistry; Combinatorial analysis; electronic tongue; Electronics; Evolution; heparan sulfates; Heparitin Sulfate; Heparitin Sulfate - chemistry; Imaging; Life Sciences; Molecular biology; Monitors; pattern recognition; Pattern Recognition, Automated; Physical Sciences; Plasmons; Polymers; Polymers - chemistry; Proteins; Science & Technology; Self assembly; Spots; Surface Plasmon Resonance; BINDING DOMAIN; NANOPARTICLE; biosensors; IDENTIFICATION; electronic tongue; LUNG-CANCER; surface plasmon resonance; EXHALED BREATH; MOLECULAR RECOGNITION; COLORIMETRIC SENSOR ARRAY; HEPARAN-SULFATE; heparan sulfates; FLUORESCENT PROTEIN; RECEPTORS; pattern recognition
• ISSN: 1433-7851; 1521-3773
• DOI: 10.1002/anie.201205346

Licking the problem: A new type of electronic tongue was constructed by self‐assembly on the surface of a surface plasmon resonance (SPR) imaging prism with combinations of simple building blocks. The resulting combinatorial array was used to detect proteins in solution (see scheme) by using SPR imaging to monitor the interactions. The signal from each spot was dependent on its composition and the protein infused, and correlated with the response of its neighbors.