Nonconvulsive status epilepticus secondary to acute porphyria crisis

Abstract Both variegate and acute intermittent porphyria can manifest with various neurological symptoms. Although acute symptomatic seizures have been previously described, they are typically tonic–clonic and focal impaired awareness seizures. Convulsive status epilepticus and epilepsia partialis c...

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Published inEpilepsy & behavior case reports Vol. 11; pp. 43 - 46
Main Authors Dawit, Sara, Bhatt, Shubhang K, Das, Devika M, Pines, Andrew R, Shiue, Harn J, Goodman, Brent P, Drazkowski, Joseph F, Sirven, Joseph I
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.01.2019
Elsevier
Subjects
Acute porphyria crisis
Anticonvulsant medication
Electroencephalogram
Neurology
Non-convulsive status epilepticus
Variegate porphyria
Anticonvulsant medication
Variegate porphyria
Electroencephalogram
Acute porphyria crisis
Non-convulsive status epilepticus
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Summary:Abstract Both variegate and acute intermittent porphyria can manifest with various neurological symptoms. Although acute symptomatic seizures have been previously described, they are typically tonic–clonic and focal impaired awareness seizures. Convulsive status epilepticus and epilepsia partialis continua are rare and have been described on a case report basis. To our knowledge, there are no previously reported cases describing non-convulsive status epilepticus (NCSE) with electroencephalogram (EEG) documentation in the setting of acute porphyria crisis. We report a unique presentation of NCSE, which resolved after administering levetiracetam in a patient with variegate porphyria, without a known seizure disorder.
ISSN:2213-3232
2213-3232
DOI:10.1016/j.ebcr.2018.11.002