PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels

We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mou...

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Published in	Bioinformatics Vol. 31; no. 16; pp. 2745 - 2747
Main Authors	Choi, Yongwook, Chan, Agnes P.
Format	Journal Article
Language	English
Published	England Oxford University Press 15.08.2015
Subjects	Access control to computer data Amino Acid Substitution - genetics Amino acids Animals Applications Notes Bioinformatics Deletion Genetic Variation Genome Humans INDEL Mutation - genetics Internet Mice Proteins Proteins - chemistry Proteins - genetics Sequence Deletion Servers (computers) Software World Wide Web
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Abstract	We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. Availability and implementation: The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org. Contact: achan@jcvi.org Supplementary information: Supplementary data are available at Bioinformatics online.
AbstractList	We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org. achan@jcvi.org Supplementary data are available at Bioinformatics online. Summary : We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. Availability and implementation : The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org . Contact: achan@jcvi.org Supplementary information: Supplementary data are available at Bioinformatics online. We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels.Availability and implementation: The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org. Supplementary information: Supplementary data are available at Bioinformatics online. We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels.UNLABELLEDWe present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels.The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org.AVAILABILITY AND IMPLEMENTATIONThe web server is freely available and open to all users with no login requirements at http://provean.jcvi.org.achan@jcvi.orgCONTACTachan@jcvi.orgSupplementary data are available at Bioinformatics online.SUPPLEMENTARY INFORMATIONSupplementary data are available at Bioinformatics online. We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. Availability and implementation: The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org. Contact: achan@jcvi.org Supplementary information: Supplementary data are available at Bioinformatics online.
Author	Chan, Agnes P. Choi, Yongwook
Author_xml	– sequence: 1 givenname: Yongwook surname: Choi fullname: Choi, Yongwook – sequence: 2 givenname: Agnes P. surname: Chan fullname: Chan, Agnes P.
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/25851949$$D View this record in MEDLINE/PubMed
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Snippet	We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool... Summary : We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the...
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SubjectTerms	Access control to computer data Amino Acid Substitution - genetics Amino acids Animals Applications Notes Bioinformatics Deletion Genetic Variation Genome Humans INDEL Mutation - genetics Internet Mice Proteins Proteins - chemistry Proteins - genetics Sequence Deletion Servers (computers) Software World Wide Web
Title	PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels
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