PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels

We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mou...

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Bibliographic Details
Published inBioinformatics Vol. 31; no. 16; pp. 2745 - 2747
Main Authors Choi, Yongwook, Chan, Agnes P.
Format Journal Article
LanguageEnglish
Published England Oxford University Press 15.08.2015
Subjects
Access control to computer data
Amino Acid Substitution - genetics
Amino acids
Animals
Applications Notes
Bioinformatics
Deletion
Genetic Variation
Genome
Humans
INDEL Mutation - genetics
Internet
Mice
Proteins
Proteins - chemistry
Proteins - genetics
Sequence Deletion
Servers (computers)
Software
World Wide Web
Online AccessGet full text

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Summary:We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. Availability and implementation: The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org. Contact:  achan@jcvi.org Supplementary information:  Supplementary data are available at Bioinformatics online.
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Associate Editor: John Hancock
ISSN:1367-4803
1367-4811
1367-4811
1460-2059
DOI:10.1093/bioinformatics/btv195