Biomechanical Characteristics and Analysis Approaches of Bone and Bone Substitute Materials

Bone has a special structure that is both stiff and elastic, and the composition of bone confers it with an exceptional mechanical property. However, bone substitute materials that are made of the same hydroxyapatite (HA) and collagen do not offer the same mechanical properties. It is important for...

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Bibliographic Details
Published inJournal of functional biomaterials Vol. 14; no. 4; p. 212
Main Authors Niu, Yumiao, Du, Tianming, Liu, Youjun
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 01.04.2023
MDPI
Subjects
Analysis
biomaterial
Biomechanical engineering
Biomechanics
Biomedical materials
Bionics
bone
Bone composition
Bone healing
Bones
Collagen
Composite materials
Hydroxyapatite
Load
Materials substitution
Mechanical loading
Mechanical properties
Mineralization
Porosity
Review
Scaffolds
Stress analysis
Substitute bone
collagen
mineralization
bone
biomechanics
biomaterial
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Summary:Bone has a special structure that is both stiff and elastic, and the composition of bone confers it with an exceptional mechanical property. However, bone substitute materials that are made of the same hydroxyapatite (HA) and collagen do not offer the same mechanical properties. It is important for bionic bone preparation to understand the structure of bone and the mineralization process and factors. In this paper, the research on the mineralization of collagen is reviewed in terms of the mechanical properties in recent years. Firstly, the structure and mechanical properties of bone are analyzed, and the differences of bone in different parts are described. Then, different scaffolds for bone repair are suggested considering bone repair sites. Mineralized collagen seems to be a better option for new composite scaffolds. Last, the paper introduces the most common method to prepare mineralized collagen and summarizes the factors influencing collagen mineralization and methods to analyze its mechanical properties. In conclusion, mineralized collagen is thought to be an ideal bone substitute material because it promotes faster development. Among the factors that promote collagen mineralization, more attention should be given to the mechanical loading factors of bone.
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These authors contributed equally to this work.
ISSN:2079-4983
2079-4983
DOI:10.3390/jfb14040212