Unraveling the Health Effects of Environmental Mixtures: An NIEHS Priority
[...]unbiased approaches (i.e., approaches that provide comprehensive characterization of exposure without an a priori hypothesis) such as the exposome are needed to move beyond "looking under the lamppost" (i.e., only measuring exposure for chemicals with available toxicology data). [...]...
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| Published in | Environmental health perspectives Vol. 121; no. 1; pp. A6 - a8 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
National Institute of Environmental Health Sciences
01.01.2013
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| Subjects | |
| Online Access | Get full text |
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| Abstract | [...]unbiased approaches (i.e., approaches that provide comprehensive characterization of exposure without an a priori hypothesis) such as the exposome are needed to move beyond "looking under the lamppost" (i.e., only measuring exposure for chemicals with available toxicology data). [...]participants in the NIEHS Mixtures Workshop discussed the importance of developing mixtures-related databases. Because it is challenging to search the literature for interactions among chemicals, there was a great deal of interest in the development of databases that would accommodate different levels of mixture study results (i.e., in vitro studies to human studies). |
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| AbstractList | [...]unbiased approaches (i.e., approaches that provide comprehensive characterization of exposure without an a priori hypothesis) such as the exposome are needed to move beyond "looking under the lamppost" (i.e., only measuring exposure for chemicals with available toxicology data). [...]participants in the NIEHS Mixtures Workshop discussed the importance of developing mixtures-related databases. Because it is challenging to search the literature for interactions among chemicals, there was a great deal of interest in the development of databases that would accommodate different levels of mixture study results (i.e., in vitro studies to human studies). |
| Audience | Academic |
| Author | Carlin, Danielle J. Birnbaum, Linda S. Woychik, Rick Rider, Cynthia V. |
| Author_xml | – sequence: 1 givenname: Danielle J. surname: Carlin fullname: Carlin, Danielle J. organization: National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, E-mail: danielle.carlin@nih.gov – sequence: 2 givenname: Cynthia V. surname: Rider fullname: Rider, Cynthia V. organization: National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, E-mail: danielle.carlin@nih.gov – sequence: 3 givenname: Rick surname: Woychik fullname: Woychik, Rick organization: National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, E-mail: danielle.carlin@nih.gov – sequence: 4 givenname: Linda S. surname: Birnbaum fullname: Birnbaum, Linda S. organization: National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, E-mail: danielle.carlin@nih.gov |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23409283$$D View this record in MEDLINE/PubMed |
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| Copyright | COPYRIGHT 2013 National Institute of Environmental Health Sciences Copyright National Institute of Environmental Health Sciences Jan 2013 2013 |
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| Notes | SourceType-Scholarly Journals-1 content type line 14 ObjectType-Editorial-2 ObjectType-Commentary-1 content type line 23 We thank C. Thompson, M. DeVito, and N. Walker for their guidance throughout the development of the NIEHS Mixtures Workshop. We also thank W. Suk for reviewing this editorial. This editorial is the work product of an employee or group of employees of the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH); however, the statements, opinions, or conclusions contained therein do not necessarily represent the statements, opinions, or conclusions of NIEHS, NIH, or the United States government. |
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| Title | Unraveling the Health Effects of Environmental Mixtures: An NIEHS Priority |
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